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Name – Biman Das Age – 28 years Indian origin, stays in Bangalore, India. 9th July 2012 - hemoglobin electrophoresis suggestive of Homozygous Hemoglobin E disease Complaint – Weakness since 1year. Hi…. Below are the complete tests I have done two days back….. Blood Urea Nitrogen – 11.00 mg/dl Serum Creatinine – 1 mg/dl Serum Glucose – 94 mg/dl SERUM LIVER FUNCTION TEST Billirubin Total – 1.30 mg/dl Billirubin – direct – 0.30 mg/dl SGOT/AST (P5P, IFCC) – 63.00 IU/ml SGPT/ALT (P5P, IFCC) – 142.00 IU/ml ALP – 74 IU/ml Total protein – 7.80 g/dl Serum Albumin – 4.90 g/dl Serum Globulin – 2.90 g/dl ALB/GLOB Ratio – 1.69 g/dl SERUM TSH (ECLIA) – 6.240 IU/mL COMPLETE BLOOD COUNT WBC – 9300.00 /cu.mm RBC – 6.15 million/cu.mm Hemoglobin – 11.90 g/dl Haemotocrit (PCV) – 37.00 % MCV – 61.00 fL MCH – 19.40 Pg MCHC – 31.30 g/dl Platelet count – 135000.00 /Cu.mm DIFFERENTIAL COUNT Neutrophils – 52 % Lymphocytes – 43 % Monocytes – 3.00 % Eosinophils – 2.00 % ESR – 4.00 /1st hour. PERIPHERAL SMEAR EXAMINATION RBC’s – Show moderate anisopoikilocytosis, are microcytic hypochromic with few eliptocytes, target cells. WBC’s – Leucocytes are normal in total count and distribution Plateletes – Plateletes are reduced. Macroplateletes noted. Impression – Microcytic hypochromic blood picture with thrombocytopenia. (Kindly correlate with serum iron,TIBC, ferritin and Hb variant analysis [To rule out hemoglobinopathy]) OTHER TESTS – Routine Urine analysis – All values are normal ECG – Normal study X-Ray of chest – PA View – Normal Study MY HABBITS – Non veg 3 days a week Beer – 3 days a week( 700ml per day) drinking since 10 years. Smoking – 12 cigarettes per day (Smoking since 10 years). More Anxiety and less physical activities. Last one year I am inside my house, just for half an hour I go outside in the morning. MY HISTORY AND TESTS DONE EARLIER – History of acidity, constipation and digestion. 9th July 2012 - Haemoglobin electrophoresis suggestive of Homozygous Haemoglobin E disease. 16th October 2012 - Ultrasound of liver – Fatty Liver 18th October 2012 – Liver function test – All values are normal 18th October 2012 – Pulmonary test – Normal spirometery 18th October 2012 – Complete Haemoglobin – Haemoglobin 12.5 gm/dl, WBC – normal in number and morphology, RBC – Anicocytosis with microcytic hypochromic erythrocytes, mild polychromasia, elliptocytes and taget cells, platelets- adequate Please let me know is it very serious and also let me know some medicines and diet... Regards Biman Das

PAST HISTORY : Homozygous Haemoglobin E disease Acidity and IBS