Name – Biman Das Age â
  Name – Biman Das Age â

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Name – Biman Das Age – 28 years Indian origin, stays in Bangalore, India. 9th July 2012 - hemoglobin electrophoresis suggestive of Homozygous Hemoglobin E disease Complaint – Weakness since 1year. Hi…. Below are the complete tests I have done two days back….. Blood Urea Nitrogen – 11.00 mg/dl Serum Creatinine – 1 mg/dl Serum Glucose – 94 mg/dl SERUM LIVER FUNCTION TEST Billirubin Total – 1.30 mg/dl Billirubin – direct – 0.30 mg/dl SGOT/AST (P5P, IFCC) – 63.00 IU/ml SGPT/ALT (P5P, IFCC) – 142.00 IU/ml ALP – 74 IU/ml Total protein – 7.80 g/dl Serum Albumin – 4.90 g/dl Serum Globulin – 2.90 g/dl ALB/GLOB Ratio – 1.69 g/dl SERUM TSH (ECLIA) – 6.240 IU/mL COMPLETE BLOOD COUNT WBC – 9300.00 /cu.mm RBC – 6.15 million/cu.mm Hemoglobin – 11.90 g/dl Haemotocrit (PCV) – 37.00 % MCV – 61.00 fL MCH – 19.40 Pg MCHC – 31.30 g/dl Platelet count – 135000.00 /Cu.mm DIFFERENTIAL COUNT Neutrophils – 52 % Lymphocytes – 43 % Monocytes – 3.00 % Eosinophils – 2.00 % ESR – 4.00 /1st hour. PERIPHERAL SMEAR EXAMINATION RBC’s – Show moderate anisopoikilocytosis, are microcytic hypochromic with few eliptocytes, target cells. WBC’s – Leucocytes are normal in total count and distribution Plateletes – Plateletes are reduced. Macroplateletes noted. Impression – Microcytic hypochromic blood picture with thrombocytopenia. (Kindly correlate with serum iron,TIBC, ferritin and Hb variant analysis [To rule out hemoglobinopathy]) OTHER TESTS – Routine Urine analysis – All values are normal ECG – Normal study X-Ray of chest – PA View – Normal Study MY HABBITS – Non veg 3 days a week Beer – 3 days a week( 700ml per day) drinking since 10 years. Smoking – 12 cigarettes per day (Smoking since 10 years). More Anxiety and less physical activities. Last one year I am inside my house, just for half an hour I go outside in the morning. MY HISTORY AND TESTS DONE EARLIER – History of acidity, constipation and digestion. 9th July 2012 - Haemoglobin electrophoresis suggestive of Homozygous Haemoglobin E disease. 16th October 2012 - Ultrasound of liver – Fatty Liver 18th October 2012 – Liver function test – All values are normal 18th October 2012 – Pulmonary test – Normal spirometery 18th October 2012 – Complete Haemoglobin – Haemoglobin 12.5 gm/dl, WBC – normal in number and morphology, RBC – Anicocytosis with microcytic hypochromic erythrocytes, mild polychromasia, elliptocytes and taget cells, platelets- adequate Please let me know is it very serious and also let me know some medicines and diet... Regards Biman Das

PAST HISTORY : Homozygous Haemoglobin E disease Acidity and IBS

2 Answers

Hi,

The values you attached show that your are suffering from microcytic and hypochromic anemia which is most commonly due to iron deficency,but you say you have haemoglobin e disese(which is not a very common diagnosis)
Rest your liver function tests show raised values and also shows long lasting effects on liver,and if you don't have any infection of liver then it is due to alcohol which you will have to decrease and try to stop it(old hepatomegaly or fatty liver is also due to the same.You can have syrup urodeoxycholic for that,but it has very less action and you will have to quit alcohol finally for looking better effects.
It does not seem to be very serious,although you will have to be precautious for your liver function tests which seems to be high and the only treatment being abstenence from alcohol.
The diet won't have much effects over your anemia,but you can avoid spicy oily food and have good vegetable diat and fruits.

Patient asked followup Question: 8 years ago

I have consulted my doctor but he have not asked for any liver infection tests like hepatitis..instead he asked me to do a thyroid antibodies test...i don't know why?...I have stopped alcohol and wont be drinking anymore in future...I also wanted to know sir that my eyes are still yellow and it has yellow from many years(Not clear like white), and little weakness is there...how much time will it take to be normal and does smoking will effect my condition...Please also tell me the list of things to avoid in any cause apart from alcohol....your advice would of great health..... Thanks, Biman Das

Hi,

I am not sure,your doctor must have examined you so he can might be telling better,but i belive you should have complet liver tests including pt aptt and coagulation profile and billirubin levels and also repeat the tests you already have.
Although yellow eyes can also be due to mddy sclera,some people have muddy sclera.
Your tsh is also raised so he might be telling you for some test or may be you could be directly be put on medicines for this.
Time taken is different for diffirent persons for improvement.
Yes you will have to quit smoking that is even more dangerous than drinking.
Without examining you i can just say yo to have a moderately good amout of protein and try to gain for the lost protein and avoid excessive and salt in your diet

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