Total Views: 781

My daughter (12yrs) is being treated for Juvenile Rheumatoid Arthiritis for the last 4yrs in Singapore. She was treated with Enbrel injection with methatrexate weekly. Then with Infliximab monthly. But still no improvement. Now our Doctor advising us to change to Humira injection. I request your advice in this regard.

1 Answers

Dr. Naval Mendiratta answered : 3 years ago

You should discuss with your doctor. I feel She is not responding to TNF Blockers. So there is no point trying the 3rd one when the first 2 failed. Discuss on the options of Tocilizumab vs Rituximab(I am not sure if it s a seropositive JRA or seronegative). But I wont suggest Humira

Have a similar question? Ask our top doctors now !

Answers
Doctors

Matching Already Answered Queries

1 Answer

I hv been having problems of dizziness, and spinning sensations since last 4/5 days. Had the same earlier abt 2 yrs back but on a very mild scale and they went away without any medication. This time it has been rather acute. Visited the physician and hv been prescribed Vertin 8 mg 1x3 times a day before bkfst, lunch and dinner. After three days feeling better but the sensations are still there albeit milder. Feel the spinning sensation especially when I look straight up/down and then bring the head back to normal posn.Again when I am changing sides on bed while lying down from left to right rpt left to right I feel the same sensation. Tho' the dizziness and the spinning sensations are less now after taking the dosages of Vertin 8 last three days would u hv any advice as to how long it takes normally for the problems to be totally eliminated? I am particularly concerned as I am, tho' a retired person, a man of fairly active habits and for the various domestic chores often hv to drive quite a bit in heavy city traffic and as a result of this problem am completely grounded which is affecting our day-to-day life styles and needs.

Doctor's Answer

Hi, Tablet Vertin is used for relief of vertigo due to several reasons, but it is to be known why is this vertigo occurring. For that reason MRI and other tests needs to be done. The possible causes could be some problem in the brain or ear. If there is chronic disease in the ear, the internal ear is effected and there will be vertigo. The duration of vertigo will depend on the cause. To prevent worsening of symptoms during episodes of vertigo, try the following: - Keep still, sit or lie dow ...
Read Full Answer

1 Answer

Sir i am suffering from knee sweeling in my rt knee for 6 month,two times i hv removed water(aspiration) from it bt never found relief.some time it decrease and some time increase.all tests x rays,crp,esr are normal not yet i found any relief.4 years ago same problem were in my lft knee and dr. Removed 2 pieces(tissue) from lft knee which were found normal(non specific),till one month after surgery i couldn't bent knee even a little bit,i took physiotherapy by wax and till 9 months i could bent it onle 80% after 1.5 or 2 year i could bent it properly 100 bt with pain,still there is pain when i bent it proper,and also swelling in rt knee.Dr.'s Of hospital in which i get surgery 4 yrs ago said that same surgery will pass in rt knee,bt i am afraid because still there is pain in my lft knee,if i pass again surgery in rt knee i will face same problem of pain in my rt knee,please advice me sir if there another way to get treated without surgery like med. Or i should get treated by surgery,i am just 23 yr old boy,still there is whole life for me to live please help me.

Doctor's Answer

Try with some good physio therapist ,with CPM and manual therapy skills. ...
Read Full Answer

2 Answers

Hello, I have had a nail fungus for a good ten years or so. When I first noticed it, I went to my doctor and he game me lamasil which I stopped taking after a few days since it had negative affects on me. Thereafter, I stopped taking care of it and just let it go for a good 7 or 8 years. I eventually grew up and started getting very self conscious of how it looked and wanted to wear sandals and flip flops and not have people think nasty things about me. A few years ago I went to my doctor again and he gave me a topical oil which I used for over a year and did not see any results. About two years ago, I noticed that a vertical brown line was starting to grow from the bottom up. I went to a dermatologist who took a sample of my nail but did not take a sample of the nail bed or from the cuticle. Biopsy came back as of course it being a fungus. He in turn gave me pills to take which I also had to stop taking since it was having a bad affect on my liver. After that, my dermatologist said that he would give me laser treatments which I did two of. They did not clear it but it looks a little bit better then what it was before. Still thick, yellow, crumbling below the nail, nail bed where new nail is growing is darker then the others and the brown line is still there. It is a thick brown line. How did I get this brown line? Did I get it because of the prolonged damage of the nail bed due to the years of having the nail fungus?

Doctor's Answer

You're most welcome. Nail Melanoma does not affect multiple nails together while Longitudunal Melanonychia (LM) often does. The fact that an additional nail is showing changes is nearly conclusive that this is LM, which as I said is harmless. However it would be best to see your doctor to get this confirmed since I cannot see the affected area. I would recommend getting the entire nail removed if its the only one affected by fungus, but this will be solely to treat the fungus not because I thin ...
Read Full Answer

1 Answer

Can homeopathy and alopathy medicine both can be taken for treatement of cronic juvenile rhematoid atritis.

Doctor's Answer

yes. Both together can give the best results , ...
Read Full Answer

1 Answer

hi i have a female friend , she used to to smoke Hookah tobacco for 3 months then suddenly she stopped smoking , now she feels heart pain (heart beats faster ), chest pain (hard to breath and some timed coughs blood ) and back pain when she went to the hospital the doctor said you must stop smoking hookah gradually not stop suddenly so what do u recommend and is it true that this is the only solution for this problem ? or is there some kind of pills or medical solution? i don't her to smoke again cause if she tries again she may be addicted again to hookah tobacco so please i want a better solution then this solution

Doctor's Answer

Hi, Since you have not told me about the age of the patient ,with only history available that she was a smoker,following might be the causes - - Bronchitis - Brochiectasis - Lung carcinoma - Pneumonia For all of these you will have to leave smoking.You may quit smoking suddenly but doctors at might not recommend it because this might suddenly lead to dropping of hormone levels in blood which might cause depression. For knowing about the exact cause about the disease, I will have to know ...
Read Full Answer

Doctors Related to