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My daughter (12yrs) is being treated for Juvenile Rheumatoid Arthiritis for the last 4yrs in Singapore. She was treated with Enbrel injection with methatrexate weekly. Then with Infliximab monthly. But still no improvement. Now our Doctor advising us to change to Humira injection. I request your advice in this regard.

You should discuss with your doctor. I feel She is not responding to TNF Blockers. So there is no point trying the 3rd one when the first 2 failed. Discuss on the options of Tocilizumab vs Rituximab(I am not sure if it s a seropositive JRA or seronegative). But I wont suggest Humira ...

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My daughter (12yrs) is being treated for Juvenile Rheumatoid Arthiritis for the last 4yrs in Singapore. She was treated with Enbrel injection with methatrexate weekly. Then with Infliximab monthly. But still no improvement. Now our Doctor advising us to change to Humira injection. I request your advice in this regard.

yes, its right decision if infliximab is failed, starts with humira... continue methotrexate ...

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Dr. Alok Kalyani

Rheumatologist
New Delhi, India
455 Doc Points

Dr. Naval Mendiratta

Rheumatologist
, India
320 Doc Points

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