I am 33 years old.i had muscle injury Around ankle due to fall 25 days back.There was no fracture but pain inflammation was done.after 5,6 days i felt more pain around my ankle and leg.my uric acid level was tested which is 7.3.i started zyloric 100mg BD.after about 12 days I checked my blood pressure which was 140/100 and my Serum cholestrol was 123 3 days back from today. What i shiuld done, plz guide me....

My father is 78 years old and has been suffering from constipation for the last 2 years. He has also lost a lot of weight around 10 kgs in this time span. In the last couple of months he has been complaining that his abdominal muscles have torn due to bowel straining and now he says there is loss of muscle in his stomach area. Which is why when he lies down everything is fine but when he sits up and walks around he feels like he is carrying a weight in his stomach. After intake of food it becomes worse and he also gets bloating. We have done all possible tests - colonoscopy, CT scan, ultrasound sometime last year and everything was clear. The doctors gave a verdict of idiopathic constipation and left it at that. His blood work is fine, haemoglobin levels, cholestrol etc. He still suffers from constipation. His prostrate is enlarged but results are fine. What is the solution to his stomach muscle problem ? Is it lack of exercise, lack of protein ? He doesnt have a pot belly and has never had and had always been physically active and fairly slender.

About 5 years ago I noticed a dramatic reduction of the muscle mass (Muscle atrophy) in my right calf muscle, like 75% to 80% reduction compared to my Left calf Muscle (possible the gastrocnemius), I also noticed that my Achilles is also very loose, when in a relaxed state, compared to the left leg. What could be the possible problems? There is no pain (other than uneasiness like restless leg syndrome) associated with this problem. I do have a lower back problem (damage) that was done 30 years ago to the L4/L5 herniated disk. Now I have noticed that other muscles are starting to harden and reduce like the one did 5 years ago. I went on a 15 mile hike in the mountains this past summer and I am very active during the day. However I do not regularly exercise as I should. Thoughts?

In my routine blood test the following three are showing higher values 1)Polymorphs 64 % 2)Triglycerides 178 3)serum VLDL CHOLESTEROL 35.6 Other values serum HDL CHOLESTEROL 50 serum LDL - CHOLESTEROL 114.4 Should there be any concern? Should I take any medication ?

Name – Biman Das Age – 28 years Indian origin, stays in Bangalore, India. 9th July 2012 - hemoglobin electrophoresis suggestive of Homozygous Hemoglobin E disease Complaint – Weakness since 1year. Hi…. Below are the complete tests I have done two days back….. Blood Urea Nitrogen – 11.00 mg/dl Serum Creatinine – 1 mg/dl Serum Glucose – 94 mg/dl SERUM LIVER FUNCTION TEST Billirubin Total – 1.30 mg/dl Billirubin – direct – 0.30 mg/dl SGOT/AST (P5P, IFCC) – 63.00 IU/ml SGPT/ALT (P5P, IFCC) – 142.00 IU/ml ALP – 74 IU/ml Total protein – 7.80 g/dl Serum Albumin – 4.90 g/dl Serum Globulin – 2.90 g/dl ALB/GLOB Ratio – 1.69 g/dl SERUM TSH (ECLIA) – 6.240 IU/mL COMPLETE BLOOD COUNT WBC – 9300.00 /cu.mm RBC – 6.15 million/cu.mm Hemoglobin – 11.90 g/dl Haemotocrit (PCV) – 37.00 % MCV – 61.00 fL MCH – 19.40 Pg MCHC – 31.30 g/dl Platelet count – 135000.00 /Cu.mm DIFFERENTIAL COUNT Neutrophils – 52 % Lymphocytes – 43 % Monocytes – 3.00 % Eosinophils – 2.00 % ESR – 4.00 /1st hour. PERIPHERAL SMEAR EXAMINATION RBC’s – Show moderate anisopoikilocytosis, are microcytic hypochromic with few eliptocytes, target cells. WBC’s – Leucocytes are normal in total count and distribution Plateletes – Plateletes are reduced. Macroplateletes noted. Impression – Microcytic hypochromic blood picture with thrombocytopenia. (Kindly correlate with serum iron,TIBC, ferritin and Hb variant analysis [To rule out hemoglobinopathy]) OTHER TESTS – Routine Urine analysis – All values are normal ECG – Normal study X-Ray of chest – PA View – Normal Study MY HABBITS – Non veg 3 days a week Beer – 3 days a week( 700ml per day) drinking since 10 years. Smoking – 12 cigarettes per day (Smoking since 10 years). More Anxiety and less physical activities. Last one year I am inside my house, just for half an hour I go outside in the morning. MY HISTORY AND TESTS DONE EARLIER – History of acidity, constipation and digestion. 9th July 2012 - Haemoglobin electrophoresis suggestive of Homozygous Haemoglobin E disease. 16th October 2012 - Ultrasound of liver – Fatty Liver 18th October 2012 – Liver function test – All values are normal 18th October 2012 – Pulmonary test – Normal spirometery 18th October 2012 – Complete Haemoglobin – Haemoglobin 12.5 gm/dl, WBC – normal in number and morphology, RBC – Anicocytosis with microcytic hypochromic erythrocytes, mild polychromasia, elliptocytes and taget cells, platelets- adequate Please let me know is it very serious and also let me know some medicines and diet... Regards Biman Das

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