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Peripheral

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89 year old mother with history of epilepsy, breast cancer, peripheral neuropathy, arthritis, atrial fibrillation, anxiety; was recently diagnosed with lung cancer. Biopsy results not in yet. Miracle drug out there somewhere?

Hello, Let the reports of biopsy come in, only then various treatment options can be considered. Rather than hoping for miracle, treatment should be considered based on scientific evidence and rationale. ...

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Name – Biman Das Age – 28 years Indian origin, stays in Bangalore, India. 9th July 2012 - hemoglobin electrophoresis suggestive of Homozygous Hemoglobin E disease Complaint – Weakness since 1year. Hi…. Below are the complete tests I have done two days back….. Blood Urea Nitrogen – 11.00 mg/dl Serum Creatinine – 1 mg/dl Serum Glucose – 94 mg/dl SERUM LIVER FUNCTION TEST Billirubin Total – 1.30 mg/dl Billirubin – direct – 0.30 mg/dl SGOT/AST (P5P, IFCC) – 63.00 IU/ml SGPT/ALT (P5P, IFCC) – 142.00 IU/ml ALP – 74 IU/ml Total protein – 7.80 g/dl Serum Albumin – 4.90 g/dl Serum Globulin – 2.90 g/dl ALB/GLOB Ratio – 1.69 g/dl SERUM TSH (ECLIA) – 6.240 IU/mL COMPLETE BLOOD COUNT WBC – 9300.00 /cu.mm RBC – 6.15 million/cu.mm Hemoglobin – 11.90 g/dl Haemotocrit (PCV) – 37.00 % MCV – 61.00 fL MCH – 19.40 Pg MCHC – 31.30 g/dl Platelet count – 135000.00 /Cu.mm DIFFERENTIAL COUNT Neutrophils – 52 % Lymphocytes – 43 % Monocytes – 3.00 % Eosinophils – 2.00 % ESR – 4.00 /1st hour. PERIPHERAL SMEAR EXAMINATION RBC’s – Show moderate anisopoikilocytosis, are microcytic hypochromic with few eliptocytes, target cells. WBC’s – Leucocytes are normal in total count and distribution Plateletes – Plateletes are reduced. Macroplateletes noted. Impression – Microcytic hypochromic blood picture with thrombocytopenia. (Kindly correlate with serum iron,TIBC, ferritin and Hb variant analysis [To rule out hemoglobinopathy]) OTHER TESTS – Routine Urine analysis – All values are normal ECG – Normal study X-Ray of chest – PA View – Normal Study MY HABBITS – Non veg 3 days a week Beer – 3 days a week( 700ml per day) drinking since 10 years. Smoking – 12 cigarettes per day (Smoking since 10 years). More Anxiety and less physical activities. Last one year I am inside my house, just for half an hour I go outside in the morning. MY HISTORY AND TESTS DONE EARLIER – History of acidity, constipation and digestion. 9th July 2012 - Haemoglobin electrophoresis suggestive of Homozygous Haemoglobin E disease. 16th October 2012 - Ultrasound of liver – Fatty Liver 18th October 2012 – Liver function test – All values are normal 18th October 2012 – Pulmonary test – Normal spirometery 18th October 2012 – Complete Haemoglobin – Haemoglobin 12.5 gm/dl, WBC – normal in number and morphology, RBC – Anicocytosis with microcytic hypochromic erythrocytes, mild polychromasia, elliptocytes and taget cells, platelets- adequate Please let me know is it very serious and also let me know some medicines and diet... Regards Biman Das

Hi, I am not sure,your doctor must have examined you so he can might be telling better,but i belive you should have complet liver tests including pt aptt and coagulation profile and billirubin levels and also repeat the tests you already have. Although yellow eyes can also be due to mddy sclera,some people have muddy sclera. Your tsh is also raised so he might be telling you for some test or may be you could be directly be put on medicines for this. Time taken is different for diffirent person ...

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Hello Sir,My father is now 72 yrs. of age.He is on 'Olmesartan medoxomil40mg' in morning and 'Metoprolol Succinate 25 mg' with 'Amlodipine 2.5 mg' in a combination in the evening for the last 3+ yrs.,and his hypertension was in control (avg. 130/85). Previously he was on only on 'Amlodipine besylate 5 mg' once a day for the last 10+ yrs.( before he started the above-mentioned medication 3 yrs. back as per his doctor's advise but when the peripheral edema and a little-bit face swelling started,and the B.P could not controlled with plain Amlodipine 5 mg,doctor advised the above-mentioned medication after closely monitoring ECG and related tests).Till last six month the B.P was in control(avg. 135/82)without any remarkable side effect except 'back of palm' & 'foot skin rash' which he had for more than last 10+ yrs. and being treated separately with skin cream (clobetasol,miconazole,gentamycin combination in S.O.S-basis with citicoline skin cream when it is too necessary to moist the skin)- but suddenly the B.P is constant on an avg. 145/92 without any major health related complain from patient except sudden-started oedema in left foot skin and left tibea-febula skin for the last 10 days,and the doctor is now suddenly not willing to further new prescription and advised 2nd consultation with another doctor.Now I'm worried what to do exactly,last 3 days I tried only Amlodipine 5 mg in evening and olmesartan 40 mg in morning and B.P is now 140/82 in an avg. for the last 3 days.Please advise me what should I do now? Expecting your kind opinion at your earliest to rule out the problem and the solution for the same. Thank you very much Sir.

hi, do not increase the bp drug dose without physician's advice your father needs further evaluation if he is compliant with drugs and not taking any new medications and on proper diet ...

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